MST-1 (Mammalian STE20-like kinase 1) is a serine/threonine kinase that has been implicated to play a role in chromatin condensation. Its C-terminal contains nuclear export signals which are released upon caspase mediated cleavage. The N-terminus portion of MST-1 then translocates to the nucleus and will promote chromatin condensation. The full length of MST-1 is localized to the cytoplasm.