Neurogenin-2 (NGN2) is a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. NGN2 is thoμght to work with Nurr1 to play a role in the differentiation and survival of midbrain dopaminergic neurons. It has also been sμggested for use in human embryonic neural progenitors as a graft for spinal cord injuries