KEY FEATURES & APPLICATIONS:
• Water-soluble
• Adds a 5-atom spacer arm (8.1 Å) to minimize steric hindrance
• The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc.
• Commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation
• Amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides
• Useful RNA-protein crosslinking reagent.
• Water-soluble
• Adds a 5-atom spacer arm (8.1 Å) to minimize steric hindrance
• The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc.
• Commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation
• Amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides
• Useful RNA-protein crosslinking reagent.