Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.