• AMG-208
  • 2553-5
  • 5 mg
AMG-708 is a selective small-molecule inhibitor (IC₅₀ = 9.3 nM) of the proto-oncogene c-Met with potential antineoplastic activity. AMG 208 inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c-Met.

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