3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.