Protein A Magnetic Beads are prepared by covalently coupling Recombinant Protein A (contains five IgG binding domain, BV catalog # 6500B) to 6% crosslinked magnetically beaded agarose. The coupling technique is optimized to give a high binding capacity for IgG. The capacity of IgG binding is generally greater than 25 mg of human IgG per ml of wet gel.