Histidine protein kinase and eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Exhibits anticancer activity in a variety of malignant cell lines (IC50 values are 0.7 - 4.8 μM) and blocks G1/S cell cycle progression. Also is an effective antibacterial agent in vitro (IC50 = 6.6 μM) and in vivo.